Source:http://linkedlifedata.com/resource/pubmed/id/12174782
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2002-8-14
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pubmed:abstractText |
A study was conducted in new patients registered with tuberculosis (TB) in a rural district of Malawi to determine (i) the prevalence of malnutrition on admission and (ii) the association between malnutrition and early mortality (defined as death within the first 4 weeks of treatment). There were 1181 patients with TB (576 men and 605 women), whose overall rate of infection with human immunodeficiency virus (HIV) was 80%. 673 TB patients (57%) were malnourished on admission (body mass index [BMI] < 18.5 kg/m2). There were 259 patients (22%) with mild malnutrition (BMI 17.0-18.4 kg/m2), 168 (14%) with moderate malnutrition (BMI 16.0-16.9 kg/m2) and 246 (21%) with severe malnutrition (BMI < 15.9 kg/m2). 95 patients (8%) died during the first 4 weeks. Significant risk factors for early mortality included increasing degrees of malnutrition, age > 35 years, and HIV seropositivity. Among all the 1181 patients, 10.9% of the 414 patients with moderate to severe malnutrition died in the first 4 weeks compared with 6.5% of the 767 patients with normal to mild malnutrition (odds ratio 1.8, 95% confidence interval 1.1-2.7). In patients with TB, BMI < 17.0 kg/m2 is associated with an increased risk of early death.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0035-9203
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
96
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
291-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12174782-AIDS-Related Opportunistic Infections,
pubmed-meshheading:12174782-Adult,
pubmed-meshheading:12174782-Aged,
pubmed-meshheading:12174782-Body Mass Index,
pubmed-meshheading:12174782-Female,
pubmed-meshheading:12174782-Humans,
pubmed-meshheading:12174782-Logistic Models,
pubmed-meshheading:12174782-Malawi,
pubmed-meshheading:12174782-Male,
pubmed-meshheading:12174782-Middle Aged,
pubmed-meshheading:12174782-Multivariate Analysis,
pubmed-meshheading:12174782-Nutrition Disorders,
pubmed-meshheading:12174782-Nutritional Status,
pubmed-meshheading:12174782-Prevalence,
pubmed-meshheading:12174782-Risk Factors,
pubmed-meshheading:12174782-Rural Health,
pubmed-meshheading:12174782-Tuberculosis
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pubmed:articleTitle |
Moderate to severe malnutrition in patients with tuberculosis is a risk factor associated with early death.
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pubmed:affiliation |
Médecins Sans Frontières-Luxembourg, Thyolo District, Malawi. zachariah@internet.lu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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