Source:http://linkedlifedata.com/resource/pubmed/id/12174675
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2002-8-14
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pubmed:abstractText |
At the present time there is an explosion of research in the area of gene arrays, and their application for detection of genes related to disease as well as its therapeutic manipulation. However, as individual arrays are expensive, comparisons of gene expression are often not repeated. In the current study, gene array experiments were repeated multiple times in order to understand the variability associated with measurements of gene expression. By focusing upon the pharmacologically important target of prostate cancer cell detachment, the current study employed multiple repeats of gene array experiments. This was used as a model system to demonstrate the utility of the experimental approach and statistical methods used.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1175-2203
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
145-52
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:12174675-Cell Adhesion,
pubmed-meshheading:12174675-Gene Expression Profiling,
pubmed-meshheading:12174675-Genetic Variation,
pubmed-meshheading:12174675-Humans,
pubmed-meshheading:12174675-Male,
pubmed-meshheading:12174675-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:12174675-Prostatic Neoplasms,
pubmed-meshheading:12174675-Tumor Cells, Cultured
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pubmed:year |
2001
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pubmed:articleTitle |
A simple analysis of gene expression and variability in gene arrays based on repeated observations.
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pubmed:affiliation |
Department of Preventive Medicine, General Clinical Research Center, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois, USA. borko@northwestern.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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