Linked Life Data

12173730

Source:http://linkedlifedata.com/resource/pubmed/id/12173730

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-8-13
pubmed:abstractText
We tested whether body mass index (BMI) and waist circumference (WC) are associated with fasting insulin in severely obese children. A number of 391 (204 female and 187 male) obese children were consecutively enrolled in the study at a Paediatric outpatient clinic. They were aged 10+/-3 yr (mean+/-SD; range: 3-17 yr) and had a relative weight for age of 160+/-27% (mean+/-SD). BMI and WC explained respectively 9 and 13% of the variance of log-transformed (lt) insulin (p<0.0001 for both). After correction for age, however, BMI lost its association with lt-insulin (p=NS) and WC explained only 3% (p<0.001) of lt-insulin variance. Sex and pubertal status did not influence the relationship between WC, BMI and lt-insulin (p=NS, ANCOVA). We conclude that in severely obese children: 1) WC is a marginally better predictor of fasting blood insulin than BMI, 2) age has a substantial influence on the relationship between BMI, WC and insulin and, 3) the contribution of BMI and WC to insulin is of doubtful clinical relevance because it leaves a substantial portion (> or = 87%) of lt-insulin variance unexplained.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0394-3402
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
160-4
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Association of waist circumference and body mass index with fasting blood insulin in severely obese children: a cross-sectional study.
pubmed:affiliation
University of Modena, Italy. giorgiobedogni@libero.it
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't