Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-8-12
pubmed:abstractText
After the reported successful use of dexmedetomidine to sedate patients in the intensive care unit without respiratory depression, we began to use dexmedetomidine for interventional neuroradiologic procedures. We report on five patients who had dexmedetomidine administered for sedation during embolization of cerebral arteriovenous malformations. All patients were comfortably sedated and breathing spontaneously. However, although patients were awake and following simple commands 10 minutes after the discontinuation of the infusion of dexmedetomidine, they were nevertheless unable to undergo cognitive testing. They were still unable to undergo cognitive testing 45 minutes after the infusion was stopped. In contrast, 10 minutes after the discontinuation of the infusion of propofol, all patients were awake, alert, cooperative, and able to undergo cognitive testing without difficulty. In conclusion, on examination of five non-randomly selected case records, we found that dexmedetomidine significantly prevented neurologic and cognitive testing.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/12172293-10702460, http://linkedlifedata.com/resource/pubmed/commentcorrection/12172293-11056756, http://linkedlifedata.com/resource/pubmed/commentcorrection/12172293-11323355, http://linkedlifedata.com/resource/pubmed/commentcorrection/12172293-11733664, http://linkedlifedata.com/resource/pubmed/commentcorrection/12172293-1361310, http://linkedlifedata.com/resource/pubmed/commentcorrection/12172293-1361311, http://linkedlifedata.com/resource/pubmed/commentcorrection/12172293-1595466, http://linkedlifedata.com/resource/pubmed/commentcorrection/12172293-1595467, http://linkedlifedata.com/resource/pubmed/commentcorrection/12172293-1675042, http://linkedlifedata.com/resource/pubmed/commentcorrection/12172293-1941114, http://linkedlifedata.com/resource/pubmed/commentcorrection/12172293-8683274, http://linkedlifedata.com/resource/pubmed/commentcorrection/12172293-9356115, http://linkedlifedata.com/resource/pubmed/commentcorrection/12172293-9606678
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0898-4921
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
209-12
pubmed:dateRevised
2011-5-17
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Dexmedetomidine may impair cognitive testing during endovascular embolization of cerebral arteriovenous malformations: a retrospective case report series.
pubmed:affiliation
Department of Anesthesiology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't