|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007634,
umls-concept:C0023089,
umls-concept:C0033572,
umls-concept:C0037813,
umls-concept:C0205148,
umls-concept:C0205183,
umls-concept:C0205282,
umls-concept:C0205307,
umls-concept:C0596801,
umls-concept:C1171362,
umls-concept:C1514893,
umls-concept:C1979963,
umls-concept:C2003903,
umls-concept:C2349975,
umls-concept:C2699488
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
2002-8-12
|
|
pubmed:abstractText |
The objective of this study was to discover protein biomarkers that differentiate malignant from nonmalignant cell populations, especially early protein alterations that signal the initiation of a developing cancer. We hypothesized that Surface Enhanced Laser Desorption/Ionization-time of flight-mass spectrometry-assisted protein profiling could detect these protein alterations.
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|
pubmed:grant |
|
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
1078-0432
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
8
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2541-52
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|
pubmed:dateRevised |
2007-11-14
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|
pubmed:meshHeading |
pubmed-meshheading:12171882-Adult,
pubmed-meshheading:12171882-Aged,
pubmed-meshheading:12171882-Humans,
pubmed-meshheading:12171882-Hyperplasia,
pubmed-meshheading:12171882-Logistic Models,
pubmed-meshheading:12171882-Male,
pubmed-meshheading:12171882-Mass Spectrometry,
pubmed-meshheading:12171882-Middle Aged,
pubmed-meshheading:12171882-Prostatic Intraepithelial Neoplasia,
pubmed-meshheading:12171882-Prostatic Neoplasms,
pubmed-meshheading:12171882-Protein Array Analysis,
pubmed-meshheading:12171882-Proteins,
pubmed-meshheading:12171882-Sensitivity and Specificity,
pubmed-meshheading:12171882-Tumor Markers, Biological
|
|
pubmed:year |
2002
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|
pubmed:articleTitle |
Normal, benign, preneoplastic, and malignant prostate cells have distinct protein expression profiles resolved by surface enhanced laser desorption/ionization mass spectrometry.
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|
pubmed:affiliation |
Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School and Sentara Cancer Institute, Norfolk, Virginia 23501, USA.
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|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
