Linked Life Data

12169234

Source:http://linkedlifedata.com/resource/pubmed/id/12169234

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2002-8-9
pubmed:abstractText
Associated with significant morbidity and mortality, atrial fibrillation is one of the most common cardiac rhythm disorders. Cure of this arrhythmia has been elusive over the years, despite development of different antiarrhythmic drugs and advances in the understanding of its pathophysiology. Initial experience with catheter ablation procedures based on the creation of linear lesions in both atria has been disappointing, but has led to the key observation that focal triggers localized in the pulmonary veins are responsible for initiation of atrial fibrillation, and thus are suitable targets for catheter ablation. With advances in technology and larger experience, it has become clear that electrical isolation of all four pulmonary veins from the left atrium provides the higher cure rates. However, the procedure is still operator dependent and is associated with a small but significant risk of pulmonary vein stenosis. Further simplification of the isolation techniques and refinement in the catheter design will allow more widespread use of this procedure and higher success rate.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1523-3782
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
379-87
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Ablation of atrial fibrillation.
pubmed:affiliation
Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Desk F15, 9500 Euclid Avenue, Cleveland, OH 44122, USA. natalea@ccf.org
pubmed:publicationType
Journal Article, Review