rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2002-8-8
|
pubmed:abstractText |
Left ventricular (LV) dilation and myocardial remodelling are hallmarks of heart failure in idiopathic dilated cardiomyopathy (DCM). Interstitial collagen is essential for LV integrity and function while degradation of collagen by collagenases, especially matrix-metalloproteinases (MMPs), are suggested to contribute to ventricular dilation. In the present study, serological markers of collagen metabolism were investigated.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
1388-9842
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
4
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
439-4
|
pubmed:dateRevised |
2011-6-8
|
pubmed:meshHeading |
pubmed-meshheading:12167381-Adult,
pubmed-meshheading:12167381-Aged,
pubmed-meshheading:12167381-Aged, 80 and over,
pubmed-meshheading:12167381-Biological Markers,
pubmed-meshheading:12167381-Cardiomyopathy, Dilated,
pubmed-meshheading:12167381-Collagen,
pubmed-meshheading:12167381-Collagenases,
pubmed-meshheading:12167381-Female,
pubmed-meshheading:12167381-Heart Failure,
pubmed-meshheading:12167381-Humans,
pubmed-meshheading:12167381-Male,
pubmed-meshheading:12167381-Matrix Metalloproteinase 1,
pubmed-meshheading:12167381-Matrix Metalloproteinases,
pubmed-meshheading:12167381-Middle Aged,
pubmed-meshheading:12167381-Myocardium,
pubmed-meshheading:12167381-Tissue Inhibitor of Metalloproteinase-1,
pubmed-meshheading:12167381-Ventricular Dysfunction, Left,
pubmed-meshheading:12167381-Ventricular Remodeling
|
pubmed:year |
2002
|
pubmed:articleTitle |
Elevated serum markers of collagen degradation in patients with mild to moderate dilated cardiomyopathy.
|
pubmed:affiliation |
Department of Cardiology, Angiology and Pneumology, Heinrich-Heine University Düsseldorf, Moorenstrasse 5, Germany. schwartzkopff@med.uni-duesseldorf.de
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|