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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2002-8-8
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pubmed:abstractText |
The transcription factor Nrf2 and its negative regulator Keap1 play important roles in transcriptional induction of a set of detoxifying and anti-oxidant enzymes. To gain an insight into our present enigma as to how cells receive oxidative and electrophilic signals and transduce them to Nrf2, we have developed a zebrafish model system for molecular toxicological studies.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2-tert-butylhydroquinone,
http://linkedlifedata.com/resource/pubmed/chemical/Adaptor Proteins, Signal Transducing,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Cytoskeletal Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Complementary,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroquinones,
http://linkedlifedata.com/resource/pubmed/chemical/Keap1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/NF-E2-Related Factor 2,
http://linkedlifedata.com/resource/pubmed/chemical/Nfe2l2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators,
http://linkedlifedata.com/resource/pubmed/chemical/Zebrafish Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1356-9597
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
807-20
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12167159-3T3 Cells,
pubmed-meshheading:12167159-Adaptor Proteins, Signal Transducing,
pubmed-meshheading:12167159-Amino Acid Sequence,
pubmed-meshheading:12167159-Animals,
pubmed-meshheading:12167159-Base Sequence,
pubmed-meshheading:12167159-Binding Sites,
pubmed-meshheading:12167159-Carrier Proteins,
pubmed-meshheading:12167159-Cytoskeletal Proteins,
pubmed-meshheading:12167159-DNA, Complementary,
pubmed-meshheading:12167159-DNA Primers,
pubmed-meshheading:12167159-DNA-Binding Proteins,
pubmed-meshheading:12167159-Hydroquinones,
pubmed-meshheading:12167159-Mice,
pubmed-meshheading:12167159-Molecular Sequence Data,
pubmed-meshheading:12167159-NF-E2-Related Factor 2,
pubmed-meshheading:12167159-Phylogeny,
pubmed-meshheading:12167159-Sequence Homology, Amino Acid,
pubmed-meshheading:12167159-Trans-Activators,
pubmed-meshheading:12167159-Zebrafish,
pubmed-meshheading:12167159-Zebrafish Proteins
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pubmed:year |
2002
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pubmed:articleTitle |
Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system.
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pubmed:affiliation |
The Center for Tsukuba Advanced Research Alliance and Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba 305-8577, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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