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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2002-8-6
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pubmed:abstractText |
Inflammation is believed to be related to the pathogenesis of nasal polyp (NP). Inducible cyclooxygenase (COX-2) and interleukin (IL) 6 are important mediators of inflammation. However, no information is available regarding the expression of these mediators in nasal polyp fibroblasts (NPFs). The inductive effects of proinflammatory cytokines (IL-1alpha or tumor necrosis factor alpha) alone or in combination with prostaglandin E(2) on IL-6 and COX-2 messenger RNA (mRNA) synthesis in NPFs were investigated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2,
http://linkedlifedata.com/resource/pubmed/chemical/Dinoprostone,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Oxytocics,
http://linkedlifedata.com/resource/pubmed/chemical/PTGS2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Prostaglandin-Endoperoxide Synthases,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0886-4470
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
128
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
945-51
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12162776-Antineoplastic Agents,
pubmed-meshheading:12162776-Cyclooxygenase 2,
pubmed-meshheading:12162776-Dinoprostone,
pubmed-meshheading:12162776-Fibroblasts,
pubmed-meshheading:12162776-Gene Expression,
pubmed-meshheading:12162776-Humans,
pubmed-meshheading:12162776-Interleukin-1,
pubmed-meshheading:12162776-Interleukin-6,
pubmed-meshheading:12162776-Isoenzymes,
pubmed-meshheading:12162776-Membrane Proteins,
pubmed-meshheading:12162776-Nasal Polyps,
pubmed-meshheading:12162776-Oxytocics,
pubmed-meshheading:12162776-Prostaglandin-Endoperoxide Synthases,
pubmed-meshheading:12162776-RNA, Messenger,
pubmed-meshheading:12162776-Tumor Necrosis Factor-alpha
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pubmed:year |
2002
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pubmed:articleTitle |
Inducible cyclooxygenase and interleukin 6 gene expressions in nasal polyp fibroblasts: possible implication in the pathogenesis of nasal polyposis.
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pubmed:affiliation |
Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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