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pubmed-article:12161250pubmed:abstractTextThere have been reports of regional differences in the activation of mitogen activated protein kinases (MAPKs) and in the induction of immediate early genes after electroconvulsive shock (ECS) in the rat brain. This study was performed to determine whether ECS induce the region-specific phosphorylation of MAPK-downstream transcription factors, ATF-2, Elk-1, c-Jun, in rat hippocampus and cerebellum. Following ECS, the phosphorylation of ATF-2 was highly increased in the hippocampus but slightly in the cerebellum. The phosphorylation of Elk-1 was increased in the cerebellum but not in the hippocampus. In contrast, the phosphorylation of c-Jun was increased only in the hippocampus. These results indicate that ECS can induce the region-specific phosphorylation of MAPK-downstream transcription factors in rat hippocampus and cerebellum.lld:pubmed
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pubmed-article:12161250pubmed:authorpubmed-author:ParkJoo-BaeJBlld:pubmed
pubmed-article:12161250pubmed:authorpubmed-author:KangUng GuUGlld:pubmed
pubmed-article:12161250pubmed:authorpubmed-author:KimYong SikYSlld:pubmed
pubmed-article:12161250pubmed:authorpubmed-author:JuhnnYong-Sun...lld:pubmed
pubmed-article:12161250pubmed:authorpubmed-author:AhnYong MinYMlld:pubmed
pubmed-article:12161250pubmed:authorpubmed-author:OhSeung...lld:pubmed
pubmed-article:12161250pubmed:authorpubmed-author:JooYeon-HoYHlld:pubmed
pubmed-article:12161250pubmed:copyrightInfoCopyright 2002 Elsevier Science Ireland Ltd.lld:pubmed
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pubmed-article:12161250pubmed:pagination9-12lld:pubmed
pubmed-article:12161250pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:12161250pubmed:articleTitleRegion-specific phosphorylation of ATF-2, Elk-1 and c-Jun in rat hippocampus and cerebellum after electroconvulsive shock.lld:pubmed
pubmed-article:12161250pubmed:affiliationDepartment of Neuropsychiatry, Eulji University School of Medicine, Seoul 139-711, South Korea.lld:pubmed
pubmed-article:12161250pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:12161250pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed