Linked Life Data

12161250

Source:http://linkedlifedata.com/resource/pubmed/id/12161250

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2002-8-5
pubmed:abstractText
There have been reports of regional differences in the activation of mitogen activated protein kinases (MAPKs) and in the induction of immediate early genes after electroconvulsive shock (ECS) in the rat brain. This study was performed to determine whether ECS induce the region-specific phosphorylation of MAPK-downstream transcription factors, ATF-2, Elk-1, c-Jun, in rat hippocampus and cerebellum. Following ECS, the phosphorylation of ATF-2 was highly increased in the hippocampus but slightly in the cerebellum. The phosphorylation of Elk-1 was increased in the cerebellum but not in the hippocampus. In contrast, the phosphorylation of c-Jun was increased only in the hippocampus. These results indicate that ECS can induce the region-specific phosphorylation of MAPK-downstream transcription factors in rat hippocampus and cerebellum.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0304-3940
pubmed:author
pubmed:copyrightInfo
Copyright 2002 Elsevier Science Ireland Ltd.
pubmed:issnType
Print
pubmed:day
23
pubmed:volume
329
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
9-12
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:12161250-Activating Transcription Factor 2, pubmed-meshheading:12161250-Animals, pubmed-meshheading:12161250-Cerebellum, pubmed-meshheading:12161250-Cyclic AMP Response Element-Binding Protein, pubmed-meshheading:12161250-DNA-Binding Proteins, pubmed-meshheading:12161250-Electroshock, pubmed-meshheading:12161250-Genes, Immediate-Early, pubmed-meshheading:12161250-Hippocampus, pubmed-meshheading:12161250-MAP Kinase Signaling System, pubmed-meshheading:12161250-Male, pubmed-meshheading:12161250-Phosphorylation, pubmed-meshheading:12161250-Proto-Oncogene Proteins, pubmed-meshheading:12161250-Proto-Oncogene Proteins c-jun, pubmed-meshheading:12161250-Rats, pubmed-meshheading:12161250-Rats, Sprague-Dawley, pubmed-meshheading:12161250-Transcription Factors, pubmed-meshheading:12161250-ets-Domain Protein Elk-1
pubmed:year
2002
pubmed:articleTitle
Region-specific phosphorylation of ATF-2, Elk-1 and c-Jun in rat hippocampus and cerebellum after electroconvulsive shock.
pubmed:affiliation
Department of Neuropsychiatry, Eulji University School of Medicine, Seoul 139-711, South Korea.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't