|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
17
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|
pubmed:dateCreated |
2002-8-5
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|
pubmed:abstractText |
The syntheses and the pregnancy-terminating activity relationships of compounds -n are reported. Compounds 5b and are found to be more potent than DL-111-a known drug having effective pregnancy-terminating activity in vitro. Further research shows compounds 5b and have the same activity as DL-111 in vivo. We also found an exciting result that they have excellent anti-implantation activity after oral administration.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Sep
|
|
pubmed:issn |
0960-894X
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
2
|
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pubmed:volume |
12
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
2411-3
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|
pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:12161145-Abortifacient Agents, Nonsteroidal,
pubmed-meshheading:12161145-Animals,
pubmed-meshheading:12161145-Drug Design,
pubmed-meshheading:12161145-Embryo, Mammalian,
pubmed-meshheading:12161145-Embryo Implantation,
pubmed-meshheading:12161145-Luteolysis,
pubmed-meshheading:12161145-Luteolytic Agents,
pubmed-meshheading:12161145-Mice,
pubmed-meshheading:12161145-Pyridines,
pubmed-meshheading:12161145-Structure-Activity Relationship,
pubmed-meshheading:12161145-Triazoles
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|
pubmed:year |
2002
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|
pubmed:articleTitle |
Non-steroidal pregnancy-terminating agents: design, synthesis and structure-activity relationships of 2-aryl-1,2,4-triazolo[1,5-a]pyridine.
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|
pubmed:affiliation |
Zhejiang University, Department of Medicinal Chemistry, College of Pharmacy, Hangzhou 310031, PR China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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