| pubmed-article:12153983 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12153983 | lifeskim:mentions | umls-concept:C0178539 | lld:lifeskim |
| pubmed-article:12153983 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:12153983 | lifeskim:mentions | umls-concept:C0020364 | lld:lifeskim |
| pubmed-article:12153983 | lifeskim:mentions | umls-concept:C0040648 | lld:lifeskim |
| pubmed-article:12153983 | lifeskim:mentions | umls-concept:C0242184 | lld:lifeskim |
| pubmed-article:12153983 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:12153983 | lifeskim:mentions | umls-concept:C0392673 | lld:lifeskim |
| pubmed-article:12153983 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:12153983 | pubmed:dateCreated | 2002-8-2 | lld:pubmed |
| pubmed-article:12153983 | pubmed:abstractText | Although it was known for a long time that oxygen deprivation leads to the transcriptional induction of the gene encoding erythropoietin, the molecular mechanisms behind this process remained enigmatic. The cloning of the hypoxia-inducible factors (HIFs), the finding that HIF-1 regulates the expression of many more genes apart from erythropoietin, and the elucidation of the oxygen-dependent mechanisms degrading the HIF alpha subunits recently led to the spectacular discovery of the molecular principles of oxygen sensing. This review aims to summarize our current knowledge of oxygen-regulated gene expression.. | lld:pubmed |
| pubmed-article:12153983 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:12153983 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:12153983 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12153983 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:12153983 | pubmed:issn | 1530-6860 | lld:pubmed |
| pubmed-article:12153983 | pubmed:author | pubmed-author:WengerRoland... | lld:pubmed |
| pubmed-article:12153983 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:12153983 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:12153983 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12153983 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12153983 | pubmed:pagination | 1151-62 | lld:pubmed |
| pubmed-article:12153983 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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| pubmed-article:12153983 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12153983 | pubmed:articleTitle | Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression. | lld:pubmed |
| pubmed-article:12153983 | pubmed:affiliation | Carl-Ludwig-Institute of Physiology, University of Leipzig, Leipzig, Germany. wenr@medizin.uni-leipzig.de | lld:pubmed |
| pubmed-article:12153983 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12153983 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:12153983 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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