Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2002-8-2
pubmed:abstractText
Clinical profile of 105 patients with cutaneous drug eruption due to antiepileptic drugs was studied between 1992-1996. Maculopapular rash was the most common presentation though significant number of patients (29.5%) had serious rashes like Stevens Johnson syndrome (SJS) and toxic epidermal necrosis (TEN). Phenytoin and carbamazepine were the two commonly implicated drugs. Significant number of our patients had liver and kidney involvement (47.34 and 21.04%, respectively). The overall prevalence of drug rash with antiepileptics in a review of 240 cases was found to be 2.5%. Patch testing with antiepileptic drugs done in 20 patients gave 60% positive results with the suspected drug. Thus patch test is a useful tool in confirming the diagnosis of drug rashes and warrants further studies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0004-5772
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
595-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Clinical spectrum of drug rashes due to antiepileptics.
pubmed:affiliation
Department of Dermatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
pubmed:publicationType
Journal Article