pubmed-article:12151104 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:12151104 | lifeskim:mentions | umls-concept:C0037864 | lld:lifeskim |
pubmed-article:12151104 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
pubmed-article:12151104 | lifeskim:mentions | umls-concept:C1171362 | lld:lifeskim |
pubmed-article:12151104 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:12151104 | lifeskim:mentions | umls-concept:C1515670 | lld:lifeskim |
pubmed-article:12151104 | lifeskim:mentions | umls-concept:C1426327 | lld:lifeskim |
pubmed-article:12151104 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
pubmed-article:12151104 | lifeskim:mentions | umls-concept:C0750729 | lld:lifeskim |
pubmed-article:12151104 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
pubmed-article:12151104 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:12151104 | pubmed:dateCreated | 2002-8-1 | lld:pubmed |
pubmed-article:12151104 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12151104 | pubmed:abstractText | AMY-1 has been identified by us as a c-Myc-binding protein and was found to stimulate c-Myc transcription activity. AMY-1 was also found to be associated with AKAP84/149 in the mitochondria in somatic cells and sperm, suggesting that it plays a role in spermatogenesis. To access the molecular function of AMY-1, a two-hybrid screening of cDNAs encoding AMY-1-binding proteins was carried out with AMY-1 as a bait using a human testis cDNA library, and a clone encoding a novel protein, AMAP-1, was obtained. The amap-1 gene was mapped at human chromosome 17q21. AMY-1 was found to bind to and be colocalized with AMAP-1 in human 293T and HeLa cells. AMAP-1 was found to be specifically expressed in the testis and expressed post-meiotically in the testis, as was AMY-1. These results suggest that both AMAP-1 and AMY-1 play roles in spermatogenesis. | lld:pubmed |
pubmed-article:12151104 | pubmed:language | eng | lld:pubmed |
pubmed-article:12151104 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12151104 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:12151104 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:12151104 | pubmed:month | Aug | lld:pubmed |
pubmed-article:12151104 | pubmed:issn | 0006-3002 | lld:pubmed |
pubmed-article:12151104 | pubmed:author | pubmed-author:ArigaHiroyosh... | lld:pubmed |
pubmed-article:12151104 | pubmed:author | pubmed-author:TairaTakahiro... | lld:pubmed |
pubmed-article:12151104 | pubmed:author | pubmed-author:Iguchi-ArigaS... | lld:pubmed |
pubmed-article:12151104 | pubmed:author | pubmed-author:YukitakeHiros... | lld:pubmed |
pubmed-article:12151104 | pubmed:author | pubmed-author:FurusawaMakot... | lld:pubmed |
pubmed-article:12151104 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:12151104 | pubmed:day | 19 | lld:pubmed |
pubmed-article:12151104 | pubmed:volume | 1577 | lld:pubmed |
pubmed-article:12151104 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:12151104 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:12151104 | pubmed:pagination | 126-32 | lld:pubmed |
pubmed-article:12151104 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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pubmed-article:12151104 | pubmed:year | 2002 | lld:pubmed |
pubmed-article:12151104 | pubmed:articleTitle | AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis. | lld:pubmed |
pubmed-article:12151104 | pubmed:affiliation | Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita-ku, Sapporo 060-0812, Japan. | lld:pubmed |
pubmed-article:12151104 | pubmed:publicationType | Journal Article | lld:pubmed |
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