Linked Life Data

12149512

Source:http://linkedlifedata.com/resource/pubmed/id/12149512

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
143
pubmed:dateCreated
2002-7-31
pubmed:abstractText
Although gene expression can be regulated in a graded or a binary fashion, the majority of eukaryotic genes are either fully activated or not expressed at all in individual cells. This binary response might be an inherent property of many eukaryotic promoters. Analysis of transcription under the control of yeast GAL1 promoter suggests, however, that graded and binary modes of transcription are not mutually exclusive, but that both can occur at the same promoter when the activity of different signaling pathways is varied. In view of that, it can be expected that forthcoming experimental studies on the combinatorial effects of signaling and transcriptional mechanisms will reveal new strategies for generating graded or binary responses.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1525-8882
pubmed:author
pubmed:issnType
Electronic
pubmed:day
30
pubmed:volume
2002
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
pe33
pubmed:dateRevised
2009-10-21
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Binary and graded responses in gene networks.
pubmed:affiliation
EMBL-EBI, Structural Genomics Group, Cambridge CB10 1SD, UK.
pubmed:publicationType
Journal Article, Review