pubmed-article:12147742 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:12147742 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:12147742 | lifeskim:mentions | umls-concept:C0038250 | lld:lifeskim |
pubmed-article:12147742 | lifeskim:mentions | umls-concept:C0011399 | lld:lifeskim |
pubmed-article:12147742 | lifeskim:mentions | umls-concept:C0871161 | lld:lifeskim |
pubmed-article:12147742 | pubmed:issue | 8 | lld:pubmed |
pubmed-article:12147742 | pubmed:dateCreated | 2002-7-30 | lld:pubmed |
pubmed-article:12147742 | pubmed:abstractText | In this study, we characterized the self-renewal capability, multi-lineage differentiation capacity, and clonogenic efficiency of human dental pulp stem cells (DPSCs). DPSCs were capable of forming ectopic dentin and associated pulp tissue in vivo. Stromal-like cells were reestablished in culture from primary DPSC transplants and re-transplanted into immunocompromised mice to generate a dentin-pulp-like tissue, demonstrating their self-renewal capability. DPSCs were also found to be capable of differentiating into adipocytes and neural-like cells. The odontogenic potential of 12 individual single-colony-derived DPSC strains was determined. Two-thirds of the single-colony-derived DPSC strains generated abundant ectopic dentin in vivo, while only a limited amount of dentin was detected in the remaining one-third. These results indicate that single-colony-derived DPSC strains differ from each other with respect to their rate of odontogenesis. Taken together, these results demonstrate that DPSCs possess stem-cell-like qualities, including self-renewal capability and multi-lineage differentiation. | lld:pubmed |
pubmed-article:12147742 | pubmed:language | eng | lld:pubmed |
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pubmed-article:12147742 | pubmed:citationSubset | D | lld:pubmed |
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pubmed-article:12147742 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12147742 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:12147742 | pubmed:month | Aug | lld:pubmed |
pubmed-article:12147742 | pubmed:issn | 0022-0345 | lld:pubmed |
pubmed-article:12147742 | pubmed:author | pubmed-author:FisherL WLW | lld:pubmed |
pubmed-article:12147742 | pubmed:author | pubmed-author:BoydeAA | lld:pubmed |
pubmed-article:12147742 | pubmed:author | pubmed-author:LUCC | lld:pubmed |
pubmed-article:12147742 | pubmed:author | pubmed-author:ShiSS | lld:pubmed |
pubmed-article:12147742 | pubmed:author | pubmed-author:GronthosSS | lld:pubmed |
pubmed-article:12147742 | pubmed:author | pubmed-author:DenBestenPP | lld:pubmed |
pubmed-article:12147742 | pubmed:author | pubmed-author:BrahimJJ | lld:pubmed |
pubmed-article:12147742 | pubmed:author | pubmed-author:ChermanNN | lld:pubmed |
pubmed-article:12147742 | pubmed:author | pubmed-author:RobeyP... | lld:pubmed |
pubmed-article:12147742 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:12147742 | pubmed:volume | 81 | lld:pubmed |
pubmed-article:12147742 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:12147742 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:12147742 | pubmed:pagination | 531-5 | lld:pubmed |
pubmed-article:12147742 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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pubmed-article:12147742 | pubmed:year | 2002 | lld:pubmed |
pubmed-article:12147742 | pubmed:articleTitle | Stem cell properties of human dental pulp stem cells. | lld:pubmed |
pubmed-article:12147742 | pubmed:affiliation | Craniofacial and Skeletal Diseases Branch, Building 30, Room 228, NIDCR, NIH, Bethesda, MD 20892, USA | lld:pubmed |
pubmed-article:12147742 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:12147742 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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