|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2002-7-30
|
|
pubmed:abstractText |
Coronary atherosclerotic disease remains the leading cause of death in the Western world. Although the exact sequence of events in this process is controversial, reactive oxygen and nitrogen species (RS) likely play an important role in vascular cell dysfunction and atherogenesis. Oxidative damage to the mitochondrial genome with resultant mitochondrial dysfunction is an important consequence of increased intracellular RS.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
1524-4539
|
|
pubmed:author |
pubmed-author:BallingerScott WSW,
pubmed-author:BurowDavid LDL,
pubmed-author:ConklinCaryl ACA,
pubmed-author:HoraistChrisC,
pubmed-author:HuZhaoyongZ,
pubmed-author:HunterGlenn CGC,
pubmed-author:Knight-LozanoCynthia ACA,
pubmed-author:LebovitzRussellR,
pubmed-author:McIntyreKenK,
pubmed-author:PattersonCamC,
pubmed-author:ReufJohannesJ,
pubmed-author:RungeMarschall SMS
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
30
|
|
pubmed:volume |
106
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
544-9
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:12147534-Animals,
pubmed-meshheading:12147534-Aorta,
pubmed-meshheading:12147534-Apolipoproteins E,
pubmed-meshheading:12147534-Arteriosclerosis,
pubmed-meshheading:12147534-DNA, Mitochondrial,
pubmed-meshheading:12147534-DNA Damage,
pubmed-meshheading:12147534-Disease Models, Animal,
pubmed-meshheading:12147534-Disease Progression,
pubmed-meshheading:12147534-Heterozygote,
pubmed-meshheading:12147534-Homozygote,
pubmed-meshheading:12147534-Humans,
pubmed-meshheading:12147534-Immunohistochemistry,
pubmed-meshheading:12147534-Mice,
pubmed-meshheading:12147534-Mice, Inbred C57BL,
pubmed-meshheading:12147534-Mice, Knockout,
pubmed-meshheading:12147534-Mitochondria,
pubmed-meshheading:12147534-Phenotype,
pubmed-meshheading:12147534-Reactive Oxygen Species,
pubmed-meshheading:12147534-Superoxide Dismutase,
pubmed-meshheading:12147534-Tyrosine
|
|
pubmed:year |
2002
|
|
pubmed:articleTitle |
Mitochondrial integrity and function in atherogenesis.
|
|
pubmed:affiliation |
Sealy Center for Molecular Cardiology and Division of Cardiology, The University of Texas Medical Branch, Galveston, Tex, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
