Source:http://linkedlifedata.com/resource/pubmed/id/12146006
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2002-7-30
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pubmed:abstractText |
A 79-year-old male was diagnosed as having a scirrhous cancer of the stomach. Carcinomatous peritonitis was suspected on abdominal CT examination and the CA19-9 showed a high level of 95 U/ml. The patient was treated with combined chemotherapy of TS-1 and CDDP. TS-1 (100 mg/day) was administered for 14 days followed by 14 days rest as one course. CDDP was administered in 24-h continuous intravenous infusion on day 8. This treatment was done every 4 weeks regularly. After 5 courses, X-ray and endoscopy examinations revealed disappearance of cancerous lesions in the stomach with an improvement in the extensibility. No cancer cell were confirmed by endoscopic biopsy, nor did a CT-scan detect carcinomatous peritonitis. The CA19-9 decreased within the normal limit. Ten months after chemotherapy was started, the patient was very healthy without a recurrence of cancer. This combined chemotherapy has administered in 8 courses, and during this period no high grade toxicities (WHO grade 3 or 4) occurred. This TS-1/CDDP chemotherapy was effective for scirrhous gastric cancer and might be administered safely even for aged patients.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cisplatin,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Combinations,
http://linkedlifedata.com/resource/pubmed/chemical/Oxonic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines,
http://linkedlifedata.com/resource/pubmed/chemical/S 1 (combination),
http://linkedlifedata.com/resource/pubmed/chemical/Tegafur
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0385-0684
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1235-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12146006-Adenocarcinoma, Scirrhous,
pubmed-meshheading:12146006-Aged,
pubmed-meshheading:12146006-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:12146006-Cisplatin,
pubmed-meshheading:12146006-Drug Administration Schedule,
pubmed-meshheading:12146006-Drug Combinations,
pubmed-meshheading:12146006-Humans,
pubmed-meshheading:12146006-Male,
pubmed-meshheading:12146006-Oxonic Acid,
pubmed-meshheading:12146006-Pyridines,
pubmed-meshheading:12146006-Remission Induction,
pubmed-meshheading:12146006-Stomach Neoplasms,
pubmed-meshheading:12146006-Tegafur
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pubmed:year |
2002
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pubmed:articleTitle |
[Complete response in an elderly patient with advanced gastric scirrhous cancer treated with combined chemotherapy of TS-1 and CDDP].
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pubmed:affiliation |
Dept. of Gastroenterology, Nagoya National Hospital.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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