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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5-6
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pubmed:dateCreated |
2002-7-29
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pubmed:abstractText |
Phospholipase A(2) (PLA(2)) catalyses the release of free fatty acids used for eicosanoid biosynthesis. We previously reported that calcium-stimulated PLA(2) activity is reduced in the brain of cocaine users and patients with schizophrenia, and have speculated that this is due to dopaminergic hyperactivity in both conditions.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0952-3278
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
479-83
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12144867-Acyltransferases,
pubmed-meshheading:12144867-Analysis of Variance,
pubmed-meshheading:12144867-Animals,
pubmed-meshheading:12144867-Brain,
pubmed-meshheading:12144867-Calcium,
pubmed-meshheading:12144867-Cerebellum,
pubmed-meshheading:12144867-Cerebral Cortex,
pubmed-meshheading:12144867-Cocaine,
pubmed-meshheading:12144867-Dopamine Uptake Inhibitors,
pubmed-meshheading:12144867-Haloperidol,
pubmed-meshheading:12144867-Lysophospholipase,
pubmed-meshheading:12144867-Male,
pubmed-meshheading:12144867-Phospholipases A,
pubmed-meshheading:12144867-Rats,
pubmed-meshheading:12144867-Rats, Sprague-Dawley
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pubmed:articleTitle |
Chronic cocaine administration reduces phospholipase A(2) activity in rat brain striatum.
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pubmed:affiliation |
Highland Psychiatric Research Foundation, UHI Millenium Institute, Inverness, Scotland. brian@hprf.org.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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