Source:http://linkedlifedata.com/resource/pubmed/id/12144523
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2002-7-29
|
| pubmed:abstractText |
A humanized version of the apoptosis-inducing mouse anti-human Fas monoclonal antibody, HFE7A, is under further development for the treatment of autoimmune diseases such as rheumatoid arthritis. We have crystallized the antigen-binding fragment (Fab) of the humanized HFE7A. The crystals belong to the orthorhombic space group P2(1)2(1)2(1) with cell dimensions a = 54.4 A, b = 82.7 A, c = 104.9 A and contain one Fab molecule in the asymmetric unit. X-ray diffraction data were collected to 2.8 A resolution.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0929-8665
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
9
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
259-63
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:12144523-Animals,
pubmed-meshheading:12144523-Antibodies, Monoclonal,
pubmed-meshheading:12144523-Antigens, CD95,
pubmed-meshheading:12144523-Crystallography, X-Ray,
pubmed-meshheading:12144523-Humans,
pubmed-meshheading:12144523-Immunoglobulin Fragments,
pubmed-meshheading:12144523-Mice
|
| pubmed:year |
2002
|
| pubmed:articleTitle |
Crystallization and preliminary x-ray studies of the Fab fragment from a humanized version of the mouse anti-human fas antibody HFE7a.
|
| pubmed:affiliation |
Biomedical Research Laboratories, Sankyo, Co., Ltd., Shinagawa, Tokyo 140-8710, Japan.
|
| pubmed:publicationType |
Journal Article
|