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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
46
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pubmed:dateCreated |
2002-7-29
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pubmed:abstractText |
Survivin is frequently expressed in various malignancies as an inhibitor of programmed cell death, while telomerase is associated with cell immortality and consequent accumulation of a malignant genetic property. We surmised that an activation of telomerase in combination with an inhibition of apoptosis might further accelerate growth of malignant tumors. To test this hypothesis, we investigated the expression of survivin and telomerase in stomach cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0172-6390
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1150-2
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:12143224-Apoptosis,
pubmed-meshheading:12143224-Cell Survival,
pubmed-meshheading:12143224-Gastrectomy,
pubmed-meshheading:12143224-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:12143224-Humans,
pubmed-meshheading:12143224-Inhibitor of Apoptosis Proteins,
pubmed-meshheading:12143224-Lymphatic Metastasis,
pubmed-meshheading:12143224-Microtubule-Associated Proteins,
pubmed-meshheading:12143224-Neoplasm Invasiveness,
pubmed-meshheading:12143224-Neoplasm Proteins,
pubmed-meshheading:12143224-Neoplasm Staging,
pubmed-meshheading:12143224-Peritoneal Neoplasms,
pubmed-meshheading:12143224-RNA, Messenger,
pubmed-meshheading:12143224-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:12143224-Stomach,
pubmed-meshheading:12143224-Stomach Neoplasms,
pubmed-meshheading:12143224-Telomerase
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pubmed:articleTitle |
An anti-apoptosis gene, survivin and telomerase expression in gastric cancer.
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pubmed:affiliation |
Department of Surgery, Kanagawa Cancer Center, School of Medicine, Yokohama City University, Japan. tsubu@lares.dti.ne.jp
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pubmed:publicationType |
Journal Article
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