Source:http://linkedlifedata.com/resource/pubmed/id/12138700
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2002-7-25
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pubmed:abstractText |
Salivary duct carcinoma (SDC) was first described by Kleinsesser in 1968 and was classified as an independent entity by the 1991 Revised World Health Organization. It is a rare but highly malignant tumor. We reviewed pathology in 49 cases of salivary adenocarcinoma, and diagnosed 6 cases as SDC. All had a rapidly enlarged mass in the parotid gland. All were men, and 4 involved facial palsy and metastasis to cervical lymph nodes. Fine needle aspiration biopsy was conducted in 3 cases, but none was diagnosed as SDC. Two had chemotherapy, but showed no effect. All underwent surgery, but only 1 survived more than 4 years. Immunohistochemically, none showed s-100 protein. Four showed PCNA and p53 protein. Highly positive cells of PCNA and p53 were found around comedo necrosis.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0030-6622
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
105
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
727-31
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pubmed:dateRevised |
2011-7-28
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pubmed:meshHeading |
pubmed-meshheading:12138700-Adenocarcinoma,
pubmed-meshheading:12138700-Aged,
pubmed-meshheading:12138700-Humans,
pubmed-meshheading:12138700-Immunohistochemistry,
pubmed-meshheading:12138700-Male,
pubmed-meshheading:12138700-Middle Aged,
pubmed-meshheading:12138700-Prognathism,
pubmed-meshheading:12138700-Proliferating Cell Nuclear Antigen,
pubmed-meshheading:12138700-Salivary Ducts,
pubmed-meshheading:12138700-Salivary Gland Neoplasms,
pubmed-meshheading:12138700-Tumor Markers, Biological,
pubmed-meshheading:12138700-Tumor Suppressor Protein p53
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pubmed:year |
2002
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pubmed:articleTitle |
[Clinicopathological study of salivary duct carcinoma].
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pubmed:affiliation |
Department of Otolaryngology, Tokyo Medical University, Tokyo.
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pubmed:publicationType |
Journal Article,
English Abstract
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