Linked Life Data

12137741

Source:http://linkedlifedata.com/resource/pubmed/id/12137741

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-7-24
pubmed:abstractText
Membrane rafts enriched in cholesterol and sphingolipids have been hypothesized to be key mediators of sorting and signaling functions of associated molecules. Apart from a limited number of biophysical studies in living cell membranes, raft-association has been defined by a simple biochemical criterion, namely the ability to partition with detergent-resistant membranes (DRMs). Here we examine the evidence for the specification of internalization mechanisms and endocytic pathways by rafts as defined by this criterion. We have surveyed the endocytic trafficking of a variety of molecules such as lipids, toxins, glycosylphosphatidylinositol (GPI)-anchored proteins, and DRM-associated transmembrane proteins.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1084-9521
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
205-14
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Endocytosis of lipid rafts: an identity crisis.
pubmed:affiliation
National Centre for Biological Sciences, UAS-GKVK Campus, GKVK P.O., Bangalore-560065, India.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't