Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-7-22
pubmed:abstractText
Although France has had a vaccination program for 40 years, since 1990, an increase in whooping cough cases with parent-infant transmission has been observed. This study prospectively assessed the frequency of Bordetella pertussis infection in adults who consulted general practitioners for a persistent cough without an evident diagnosis. Among 217 patients, 70 (32%) confirmed whooping cough cases were identified. One case was culture positive, 36 were polymerase chain reaction positive, and 40 had increases or decreases of > or =2-fold in anti-pertussis toxin IgG titer between serum samples collected during the acute and convalescent phases. The median duration of cough in confirmed cases was 49 days (range, 13-123 days). Of the patients, 60% reported vaccination, and 33% reported whooping cough in infancy. Pertussis should be considered for diagnosis of acute and chronic cough in adults. Future studies should evaluate the public health interest of booster doses of pertussis vaccine in adults.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0022-1899
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
186
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
415-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:12134239-Adolescent, pubmed-meshheading:12134239-Adult, pubmed-meshheading:12134239-Aged, pubmed-meshheading:12134239-Aged, 80 and over, pubmed-meshheading:12134239-Antibodies, Bacterial, pubmed-meshheading:12134239-Bacterial Vaccines, pubmed-meshheading:12134239-Bordetella pertussis, pubmed-meshheading:12134239-DNA, Bacterial, pubmed-meshheading:12134239-Enzyme-Linked Immunosorbent Assay, pubmed-meshheading:12134239-Female, pubmed-meshheading:12134239-Humans, pubmed-meshheading:12134239-Male, pubmed-meshheading:12134239-Middle Aged, pubmed-meshheading:12134239-Paris, pubmed-meshheading:12134239-Polymerase Chain Reaction, pubmed-meshheading:12134239-Prospective Studies, pubmed-meshheading:12134239-Sputum, pubmed-meshheading:12134239-Statistics, Nonparametric, pubmed-meshheading:12134239-Vaccination, pubmed-meshheading:12134239-Whooping Cough
pubmed:year
2002
pubmed:articleTitle
Evidence of Bordetella pertussis infection in adults presenting with persistent cough in a french area with very high whole-cell vaccine coverage.
pubmed:affiliation
Département de Médecine Générale, Faculté de Médecine Necker-Enfants Malades, Paris, France. gilberg@necker.fr
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't