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pubmed-article:12131208pubmed:abstractTextThe CD4 T cells in mucosal subepithelia are the first cells to become infected during sexual transmission of HIV-1. Dendritic cells (DC) are located in the same area and are known to play a central role in antiviral immune responses. However, extensive viral replication, syncytia formation and cell death follows the interaction between T cells and DC previously exposed to HIV-1. Despite this, anti-HIV responses are generated that control viremia following acute infection.lld:pubmed
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pubmed-article:12131208pubmed:articleTitleActivation of HIV-1 specific CD4 and CD8 T cells by human dendritic cells: roles for cross-presentation and non-infectious HIV-1 virus.lld:pubmed
pubmed-article:12131208pubmed:affiliationThe Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York 10021, USA.lld:pubmed
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