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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2002-7-19
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pubmed:abstractText |
Intoxications with organophosphorous compounds such as paraoxon, an inhibitor of serine hydrolases, mainly butyrylcholinesterase and acetylcholinesterase, are frequent. Oximes are the only enzyme reactivators clinically available. In vitro studies have shown that L(+)-lactate reduces the inhibition of acetylcholinesteratic (AChEA) and butyrylcholinesteratic activity of plasma (BChEA) by paraoxon.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0090-3493
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1547-52
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12130977-Acetylcholinesterase,
pubmed-meshheading:12130977-Animals,
pubmed-meshheading:12130977-Butyrylcholinesterase,
pubmed-meshheading:12130977-Cholinesterase Inhibitors,
pubmed-meshheading:12130977-Female,
pubmed-meshheading:12130977-Injections, Intravenous,
pubmed-meshheading:12130977-Lactic Acid,
pubmed-meshheading:12130977-Paraoxon,
pubmed-meshheading:12130977-Swine, Miniature
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pubmed:year |
2002
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pubmed:articleTitle |
Intravenous L-lactate application in minipigs partially protects acetylcholinesteratic but not butyrylcholinesteratic activity in plasma from inhibition by paraoxon.
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pubmed:affiliation |
Institute of Pharmacology and Toxicology, University of Heidelberg at Mannheim, Mannheim, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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