Source:http://linkedlifedata.com/resource/pubmed/id/12121189
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2002-7-17
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pubmed:abstractText |
IgE-dependent triggering of basophils not only elicits the release of different mediators but also the up-regulation of certain markers, e.g. CD63, which can be detected by flow cytometry. We intended to investigate if flow cytometric analysis of basophil activation could be a valuable tool in the diagnosis of latex allergy, and to evaluate if the basophil activation test (BAT) could be helpful in determining the clinical significance of a positive latex IgE in individuals with negative history and negative latex skin test. Additionally we aimed to determine the role of cross-reactive carbohydrate determinants (CCDs) in causing positive latex IgE without apparent clinical significance.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0105-4538
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
706-12
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12121189-Basophils,
pubmed-meshheading:12121189-Bromelains,
pubmed-meshheading:12121189-Carbohydrates,
pubmed-meshheading:12121189-Cross Reactions,
pubmed-meshheading:12121189-Epitopes,
pubmed-meshheading:12121189-Flow Cytometry,
pubmed-meshheading:12121189-Humans,
pubmed-meshheading:12121189-Immunoglobulin E,
pubmed-meshheading:12121189-Latex Hypersensitivity
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pubmed:year |
2002
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pubmed:articleTitle |
Validation of a two-color flow cytometric assay detecting in vitro basophil activation for the diagnosis of IgE-mediated natural rubber latex allergy.
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pubmed:affiliation |
Department of Immunology, Allergology and Rheumatology, University of Antwerp (UIA), Belgium.
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pubmed:publicationType |
Journal Article,
In Vitro,
Validation Studies
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