Linked Life Data

12116

Source:http://linkedlifedata.com/resource/pubmed/id/12116

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1977-2-24
pubmed:abstractText
The preoperative screening and postoperative case records of two patients that underwent vascularised Fallopian tube transplants are described. In both cases the operation was followed by immunological rejection. This was chronic and clinically quiescent in the first patient, but an accelerated rejection associated with a pyrexial illness and a rise in serum fibrinogen, blood platelet and serum lactic dehydrogenase levels was observed in the second case. Technical feasibility was demonstrated but further progress in the field of Fallopian tube transplants will be dependent on the development of safer techniques of immunosuppression considered necessary for graft survival.
pubmed:keyword
http://linkedlifedata.com/resource/pubmed/keyword/Biology, http://linkedlifedata.com/resource/pubmed/keyword/Case Studies, http://linkedlifedata.com/resource/pubmed/keyword/Fallopian Tubes, http://linkedlifedata.com/resource/pubmed/keyword/Genitalia, http://linkedlifedata.com/resource/pubmed/keyword/Genitalia, Female, http://linkedlifedata.com/resource/pubmed/keyword/Infertility, http://linkedlifedata.com/resource/pubmed/keyword/Physiology, http://linkedlifedata.com/resource/pubmed/keyword/Reproduction, http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology, http://linkedlifedata.com/resource/pubmed/keyword/Studies, http://linkedlifedata.com/resource/pubmed/keyword/Surgery, http://linkedlifedata.com/resource/pubmed/keyword/Treatment, http://linkedlifedata.com/resource/pubmed/keyword/Urogenital System
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0020-725X
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
147-52
pubmed:dateRevised
2004-11-17
pubmed:otherAbstract
PIP: The 1st 2 cases of vascularized Fallopian tube transplants were performed at Groote Schuur Hospital in Cape Town, South Africa. In both cases, it was determined that the tubal defect was the only barrier to conception. The donors, both 36 years of age, had been scheduled for hysterectomy and had consented to donation of their oviducts. The 1st patient was discharged on the 16th postoperative day with no symptoms or signs of rejection of the graft. However, a hysterosalpingogram performed 3 months later showed cornual patency associated with narrowing and shrinkage of the graft specimen; the rejected tube was excised. In the 2nd case the patient developed a fever and tenderness localized to the right subcostal area. A subcostal exploration was performed, and a section of the large bowel and edematous omentum were adherent over the pelvis with bloodstained fluid in the abdomen. The graft cornu was excised, and it was necessary to remove the patient's right ovary. The occurrence of rejection indicated that the transplanted tubes had been revascularized. Rejection in both patients was associated with anatomical isolation of the graft by the omentum. Further progress in immunosuppressive therapy will be necessary for Fallopian tube transplants.
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Preliminary experience with vascularised Fallopian tube transplants in the human female.
pubmed:publicationType
Journal Article, Case Reports