Source:http://linkedlifedata.com/resource/pubmed/id/12115889
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
2002-7-12
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| pubmed:abstractText |
The courtship solicitation display (CSD) of the female canary is a model to study estrogen dependent auditory preferences for male songs. The forebrain auditory-vocal nucleus, HVC, is part of the circuit that determines such preferences. To further develop this model we show that bilateral excitotoxic lesions of the medial part of HVC involving between 18-60% of the bilateral nucleus are behaviorally effective while complete unilateral lesions are not. Further, we show that animals recover their song preferences over a period of several months after the lesion. This functional recovery does not involve anatomical recovery of the HVC. Even 9 months after the lesion, the HVC size of these females was similar to that of females sacrificed 2 days after the lesion and thus was 40 +/- 8% smaller compared to normal females. Further, ipsilaterally, the lesion procedure transiently disturbed the neurochemistry, such as GAD-mRNA expression, in the part of HVC that did not undergo cell death. These results suggest that the integrity of the lateral part of at least one HVC is required to perform CSD in response to relevant auditory stimuli.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0022-3034
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| pubmed:author | |
| pubmed:copyrightInfo |
Copyright 2002 Wiley Periodicals, Inc.
|
| pubmed:issnType |
Print
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| pubmed:volume |
52
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
1-13
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| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:12115889-Animals,
pubmed-meshheading:12115889-Brain Chemistry,
pubmed-meshheading:12115889-Canaries,
pubmed-meshheading:12115889-Cognition,
pubmed-meshheading:12115889-Copulation,
pubmed-meshheading:12115889-Denervation,
pubmed-meshheading:12115889-Female,
pubmed-meshheading:12115889-Functional Laterality,
pubmed-meshheading:12115889-Glutamate Decarboxylase,
pubmed-meshheading:12115889-Neurotoxins,
pubmed-meshheading:12115889-RNA, Messenger,
pubmed-meshheading:12115889-Receptors, Androgen,
pubmed-meshheading:12115889-Recovery of Function,
pubmed-meshheading:12115889-Telencephalon,
pubmed-meshheading:12115889-Vocalization, Animal
|
| pubmed:year |
2002
|
| pubmed:articleTitle |
Recovery of song preferences after excitotoxic HVC lesion in female canaries.
|
| pubmed:affiliation |
Laboratoire de Psychophysiologie et d'Ethologie, Université Paris X., 92000 Nanterre, France. frederique.halle@u-Paris10.fr
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| pubmed:publicationType |
Journal Article
|