12115481

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Subject	Predicate	Object	Context
pubmed-article:12115481	rdf:type	pubmed:Citation	lld:pubmed
pubmed-article:12115481	lifeskim:mentions	umls-concept:C0007600	lld:lifeskim
pubmed-article:12115481	lifeskim:mentions	umls-concept:C0086418	lld:lifeskim
pubmed-article:12115481	lifeskim:mentions	umls-concept:C0035820	lld:lifeskim
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pubmed-article:12115481	lifeskim:mentions	umls-concept:C1513095	lld:lifeskim
pubmed-article:12115481	lifeskim:mentions	umls-concept:C0007580	lld:lifeskim
pubmed-article:12115481	lifeskim:mentions	umls-concept:C2826293	lld:lifeskim
pubmed-article:12115481	pubmed:issue	6	lld:pubmed
pubmed-article:12115481	pubmed:dateCreated	2002-7-12	lld:pubmed
pubmed-article:12115481	pubmed:abstractText	Galectin-9 expression was examined in 6 human melanoma cell lines. Among them, MM-BP proliferated with colony formation, but MM-RU failed. RT-PCR analysis revealed evident expression of galectin-9 mRNA in MM-BP but not in MM-RU. MM-BP expressed galectin-9 protein both on the surface and in the cytoplasm, whereas MM-RU expressed it only weakly in the cytoplasm. Exogenous galectin-9 induced in vitro both cell aggregation and apoptosis of MM-RU proliferating without colony formation. Association of galectin-9 expression in melanoma cells with prognosis of the patients bearing melanocytic tumors was further examined. Galectin-9 protein was strongly and homogeneously expressed in melanocytic nevi, but down-regulated in melanoma cells especially in metastatic lesions. High galectin-9 expression was inversely correlated with the progression of this disease, suggesting that high galectin-9 expression in primary melanoma lesions links to a better prognosis.	lld:pubmed
pubmed-article:12115481	pubmed:language	eng	lld:pubmed
pubmed-article:12115481	pubmed:journal	http://linkedlifedata.com/r...	lld:pubmed
pubmed-article:12115481	pubmed:citationSubset	IM	lld:pubmed
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pubmed-article:12115481	pubmed:status	MEDLINE	lld:pubmed
pubmed-article:12115481	pubmed:month	Jun	lld:pubmed
pubmed-article:12115481	pubmed:issn	0020-7136	lld:pubmed
pubmed-article:12115481	pubmed:author	pubmed-author:NishiNozomuN	lld:pubmed
pubmed-article:12115481	pubmed:author	pubmed-author:ShojiHirokiH	lld:pubmed
pubmed-article:12115481	pubmed:author	pubmed-author:HirashimaMits...	lld:pubmed
pubmed-article:12115481	pubmed:author	pubmed-author:NakamuraTakan...	lld:pubmed
pubmed-article:12115481	pubmed:author	pubmed-author:KashioYumikoY	lld:pubmed
pubmed-article:12115481	pubmed:author	pubmed-author:SekiMasakoM	lld:pubmed
pubmed-article:12115481	pubmed:author	pubmed-author:YamauchiAkira...	lld:pubmed
pubmed-article:12115481	pubmed:author	pubmed-author:KageshitaTosh...	lld:pubmed
pubmed-article:12115481	pubmed:author	pubmed-author:OnoTomomichiT	lld:pubmed
pubmed-article:12115481	pubmed:author	pubmed-author:AbedinMohamma...	lld:pubmed
pubmed-article:12115481	pubmed:copyrightInfo	Copyright 2002 Wiley-Liss, Inc.	lld:pubmed
pubmed-article:12115481	pubmed:issnType	Print	lld:pubmed
pubmed-article:12115481	pubmed:day	20	lld:pubmed
pubmed-article:12115481	pubmed:volume	99	lld:pubmed
pubmed-article:12115481	pubmed:owner	NLM	lld:pubmed
pubmed-article:12115481	pubmed:authorsComplete	Y	lld:pubmed
pubmed-article:12115481	pubmed:pagination	809-16	lld:pubmed
pubmed-article:12115481	pubmed:dateRevised	2007-7-24	lld:pubmed
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pubmed-article:12115481	pubmed:year	2002	lld:pubmed
pubmed-article:12115481	pubmed:articleTitle	Possible role of galectin-9 in cell aggregation and apoptosis of human melanoma cell lines and its clinical significance.	lld:pubmed
pubmed-article:12115481	pubmed:affiliation	Department of Dermatology, Kumamoto University Medical School, Kumamoto, Japan. toshiro@kaiju.medic.kumamoto-u.ac.jp	lld:pubmed
pubmed-article:12115481	pubmed:publicationType	Journal Article	lld:pubmed
pubmed-article:12115481	pubmed:publicationType	Research Support, Non-U.S. Gov't	lld:pubmed
entrez-gene:3965	entrezgene:pubmed	pubmed-article:12115481	lld:entrezgene
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