rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2002-7-12
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pubmed:abstractText |
A high frequency of genetic alterations of the von Hippel-Lindau (VHL) gene and overexpression of the vascular endothelial growth factor (VEGF) gene have been observed independently in human sporadic renal cell carcinoma (RCCs), but to the authors' knowledge the association between the two has not been characterized in primary sporadic RCC. In the current study the authors report the simultaneous comparison of the biallelic inactivation status of the VHL gene and VEGF expression levels in patients with sporadic RCC.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Endothelial Growth Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Ligases,
http://linkedlifedata.com/resource/pubmed/chemical/Lymphokines,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Ubiquitin-Protein Ligases,
http://linkedlifedata.com/resource/pubmed/chemical/VHL protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Von Hippel-Lindau Tumor Suppressor...
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2002 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
47-53
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12115316-Adult,
pubmed-meshheading:12115316-Aged,
pubmed-meshheading:12115316-Carcinoma, Renal Cell,
pubmed-meshheading:12115316-Endothelial Growth Factors,
pubmed-meshheading:12115316-Female,
pubmed-meshheading:12115316-Humans,
pubmed-meshheading:12115316-Kidney Neoplasms,
pubmed-meshheading:12115316-Ligases,
pubmed-meshheading:12115316-Loss of Heterozygosity,
pubmed-meshheading:12115316-Lymphokines,
pubmed-meshheading:12115316-Male,
pubmed-meshheading:12115316-Middle Aged,
pubmed-meshheading:12115316-RNA, Messenger,
pubmed-meshheading:12115316-Tumor Suppressor Proteins,
pubmed-meshheading:12115316-Ubiquitin-Protein Ligases,
pubmed-meshheading:12115316-Vascular Endothelial Growth Factor A,
pubmed-meshheading:12115316-Vascular Endothelial Growth Factors,
pubmed-meshheading:12115316-Von Hippel-Lindau Tumor Suppressor Protein
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pubmed:year |
2002
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pubmed:articleTitle |
Vascular endothelial growth factor overexpression is correlated with von Hippel-Lindau tumor suppressor gene inactivation in patients with sporadic renal cell carcinoma.
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pubmed:affiliation |
Department of Pathology, Nihon University School of Medicine, Tokyo, Japan.
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pubmed:publicationType |
Journal Article
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