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pubmed-article:12115181pubmed:abstractTextRheumatoid arthritis (RA) is a chronic inflammatory disease characterized by a hyperplastic synovial tissue, inflammatory infiltrates, and a progressive destruction of cartilage and bone. FLICE-inhibitory protein (FLIP) prevents the association of caspase 8 with FADD and thus exerts an antiapoptotic effect through inhibition of Fas-mediated apoptosis. We undertook this study to examine the expression of FLIP in RA, osteoarthritic (OA), and normal synovial tissues.lld:pubmed
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pubmed-article:12115181pubmed:articleTitleFLICE-inhibitory protein expression in synovial fibroblasts and at sites of cartilage and bone erosion in rheumatoid arthritis.lld:pubmed
pubmed-article:12115181pubmed:affiliationCenter of Experimental Rheumatology, WHO Collaborating Center for Molecular Biology, University Hospital of Zurich, Gloriastrasse 25, CH-8091 Zurich, Switzerland. joerg.schedel@klinik.uni-regensburg.delld:pubmed
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