12114423

Source:http://linkedlifedata.com/resource/pubmed/id/12114423

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0282523, umls-concept:C0376452, umls-concept:C0439064, umls-concept:C0751606
pubmed:issue	7
pubmed:dateCreated	2002-7-12
pubmed:abstractText	Aberrant methylation of promoter-associated CpG islands is an epigenetic oncogenic mechanism. The objective of this study was to define the methylation characteristics of patients with acute lymphocytic leukemia (ALL).
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/P01CA49639
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9502500
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Cyclophosphamide, http://linkedlifedata.com/resource/pubmed/chemical/DNA, Neoplasm, http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers, http://linkedlifedata.com/resource/pubmed/chemical/Dexamethasone, http://linkedlifedata.com/resource/pubmed/chemical/Doxorubicin, http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological, http://linkedlifedata.com/resource/pubmed/chemical/Vincristine
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	1078-0432
pubmed:author	pubmed-author:DanielJerryJ, pubmed-author:Garcia-ManeroGuillermoG, pubmed-author:IssaJean-Pierre JJP, pubmed-author:KantarjianHagop MHM, pubmed-author:KornblauSteven MSM, pubmed-author:LeeMing-ShengMS, pubmed-author:SmithTerry LTL
pubmed:issnType	Print
pubmed:volume	8
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2217-24
pubmed:dateRevised	2008-11-21
pubmed:meshHeading	pubmed-meshheading:12114423-Adult, pubmed-meshheading:12114423-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:12114423-CpG Islands, pubmed-meshheading:12114423-Cyclophosphamide, pubmed-meshheading:12114423-DNA, Neoplasm, pubmed-meshheading:12114423-DNA Methylation, pubmed-meshheading:12114423-DNA Primers, pubmed-meshheading:12114423-Dexamethasone, pubmed-meshheading:12114423-Doxorubicin, pubmed-meshheading:12114423-Female, pubmed-meshheading:12114423-Humans, pubmed-meshheading:12114423-Male, pubmed-meshheading:12114423-Neoplasm Proteins, pubmed-meshheading:12114423-Polymerase Chain Reaction, pubmed-meshheading:12114423-Precursor Cell Lymphoblastic Leukemia-Lymphoma, pubmed-meshheading:12114423-Promoter Regions, Genetic, pubmed-meshheading:12114423-Tumor Markers, Biological, pubmed-meshheading:12114423-Vincristine
pubmed:year	2002
pubmed:articleTitle	DNA methylation of multiple promoter-associated CpG islands in adult acute lymphocytic leukemia.
pubmed:affiliation	Departments of Leukemia, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA. ggarciam@mdanderson.org
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't