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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2002-7-11
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pubmed:abstractText |
The generation during hemodialysis of activated complement fragments and reactive oxygen species, including nitric oxide (NO), may affect peripheral blood mononuclear cell (PBMC) function. Currently, little is known about signal transduction pathways involved in PBMC activation. Jun N-terminal kinase (JNK) is a novel mitogen-activated protein (MAP) kinase phosphorylated and activated in response to oxidative stress and directly involved in cell activation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antioxidants,
http://linkedlifedata.com/resource/pubmed/chemical/Complement Membrane Attack Complex,
http://linkedlifedata.com/resource/pubmed/chemical/JNK Mitogen-Activated Protein...,
http://linkedlifedata.com/resource/pubmed/chemical/Membranes, Artificial,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/NOS2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type II,
http://linkedlifedata.com/resource/pubmed/chemical/Vitamin E
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
602-10
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pubmed:dateRevised |
2011-10-27
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pubmed:meshHeading |
pubmed-meshheading:12110024-Adult,
pubmed-meshheading:12110024-Aged,
pubmed-meshheading:12110024-Antioxidants,
pubmed-meshheading:12110024-Complement Membrane Attack Complex,
pubmed-meshheading:12110024-Enzyme Activation,
pubmed-meshheading:12110024-Female,
pubmed-meshheading:12110024-Gene Expression,
pubmed-meshheading:12110024-Humans,
pubmed-meshheading:12110024-JNK Mitogen-Activated Protein Kinases,
pubmed-meshheading:12110024-Kidney Failure, Chronic,
pubmed-meshheading:12110024-Leukocyte Count,
pubmed-meshheading:12110024-Leukocytes, Mononuclear,
pubmed-meshheading:12110024-Male,
pubmed-meshheading:12110024-Membranes, Artificial,
pubmed-meshheading:12110024-Middle Aged,
pubmed-meshheading:12110024-Mitogen-Activated Protein Kinases,
pubmed-meshheading:12110024-Nitric Oxide Synthase,
pubmed-meshheading:12110024-Nitric Oxide Synthase Type II,
pubmed-meshheading:12110024-Phosphorylation,
pubmed-meshheading:12110024-Renal Dialysis,
pubmed-meshheading:12110024-Vitamin E
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pubmed:year |
2002
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pubmed:articleTitle |
Vitamin E-modified filters modulate Jun N-terminal kinase activation in peripheral blood mononuclear cells.
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pubmed:affiliation |
Division of Nephrology, Department of Emergency and Organ Transplantation, University of Bari, Polyclinic, Bari, Italy. g.pertosa@nephro.uniba.it
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pubmed:publicationType |
Journal Article,
Clinical Trial,
In Vitro,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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