rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2002-7-11
|
pubmed:abstractText |
Unlike the many chemotherapeutic agents that do not effectively stop blood flow or induce necrosis in hepatocellular carcinoma, AC-7700 has been shown to inhibit tubulin polymerization and selectively stop tumor blood flow. The aim of this study was to elucidate the antivascular and antitumor effects of AC-7700 on rat hepatoma.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
1341-9625
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
7
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
171-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12109519-Angiogenesis Inhibitors,
pubmed-meshheading:12109519-Animals,
pubmed-meshheading:12109519-Antineoplastic Agents,
pubmed-meshheading:12109519-Disease Models, Animal,
pubmed-meshheading:12109519-Liver Neoplasms, Experimental,
pubmed-meshheading:12109519-Male,
pubmed-meshheading:12109519-Neoplasm Transplantation,
pubmed-meshheading:12109519-Neovascularization, Pathologic,
pubmed-meshheading:12109519-Rats,
pubmed-meshheading:12109519-Serine,
pubmed-meshheading:12109519-Survival Rate,
pubmed-meshheading:12109519-Tubulin,
pubmed-meshheading:12109519-Tumor Cells, Cultured
|
pubmed:year |
2002
|
pubmed:articleTitle |
Antitumor and antivascular effects of AC-7700, a combretastatin A-4 derivative, against rat liver cancer.
|
pubmed:affiliation |
First Department of Surgery, Oita Medical University, Japan. oono@oita-med.ac.jp
|
pubmed:publicationType |
Journal Article,
Comparative Study
|