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rdf:type |
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lifeskim:mentions |
umls-concept:C0012634,
umls-concept:C0021641,
umls-concept:C0030705,
umls-concept:C0242692,
umls-concept:C0332307,
umls-concept:C0681850,
umls-concept:C1518469,
umls-concept:C1550501,
umls-concept:C1706203,
umls-concept:C1710082,
umls-concept:C2349001,
umls-concept:C2697811
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pubmed:issue |
6
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pubmed:dateCreated |
2002-7-10
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pubmed:abstractText |
Alterations in insulin signalling could contribute to insulin resistance in Type II (non-insulin-dependent) diabetes mellitus. Some of these alterations could be secondary to the diabetic state, ie. the hyperglycaemia or increased NEFA concentrations. We sought to exclude such secondary factors and to investigate whether Type II diabetes in itself is associated with altered insulin signalling in skeletal muscle.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, Nonesterified,
http://linkedlifedata.com/resource/pubmed/chemical/Glycogen Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/IRS1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin Receptor Substrate Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylinositol 3-Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/insulin receptor tyrosine kinase
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0012-186X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
813-22
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:12107725-Adult,
pubmed-meshheading:12107725-Biopsy,
pubmed-meshheading:12107725-Blood Glucose,
pubmed-meshheading:12107725-Body Mass Index,
pubmed-meshheading:12107725-Diabetes Mellitus,
pubmed-meshheading:12107725-Diabetes Mellitus, Type 2,
pubmed-meshheading:12107725-Enzyme Activation,
pubmed-meshheading:12107725-Family,
pubmed-meshheading:12107725-Fatty Acids, Nonesterified,
pubmed-meshheading:12107725-Female,
pubmed-meshheading:12107725-Glucose Clamp Technique,
pubmed-meshheading:12107725-Glycogen Synthase,
pubmed-meshheading:12107725-Humans,
pubmed-meshheading:12107725-Hyperinsulinism,
pubmed-meshheading:12107725-Insulin,
pubmed-meshheading:12107725-Insulin Receptor Substrate Proteins,
pubmed-meshheading:12107725-Kinetics,
pubmed-meshheading:12107725-Male,
pubmed-meshheading:12107725-Middle Aged,
pubmed-meshheading:12107725-Muscle, Skeletal,
pubmed-meshheading:12107725-Obesity,
pubmed-meshheading:12107725-Phosphatidylinositol 3-Kinases,
pubmed-meshheading:12107725-Phosphoproteins,
pubmed-meshheading:12107725-Protein-Tyrosine Kinases,
pubmed-meshheading:12107725-Reference Values,
pubmed-meshheading:12107725-Signal Transduction
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pubmed:year |
2002
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pubmed:articleTitle |
Insulin signalling in skeletal muscle of subjects with or without Type II-diabetes and first degree relatives of patients with the disease.
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pubmed:affiliation |
Department of Internal Medicine, Medical University Lübeck, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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