Linked Life Data

12107586

Source:http://linkedlifedata.com/resource/pubmed/id/12107586

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2002-7-10
pubmed:abstractText
Vessel oxygen saturation can be determined with MR oximetry using an in vivo measurement of signal decay (T2) and the calibration curve relating T2 to blood oxygen saturation (%HbO(2)), where: 1/T2=1/T2O+K (1-%HbO(2)/100)(2) and K is a constant parameter which correlates with measured fibrinogen levels. The ability to noninvasively measure %HbO(2) in cardiac chambers and vessels has enormous potential in children with congenital heart disease (CHD). Objective: The purpose of the study was to prospectively characterize the T2-%HbO(2) relationship in infants where T2-%HbO(2) is the relationship between T2 and %HbO(2) (blood oxygen saturation) expressed by the equation given above, and to determine whether adult values for K and T2O (where T2O is the T2 of fully oxygenated blood) can be extrapolated to pediatric patients with CHD. A second objective was to apply this method to calculate the %HbO(2) in vivo using MR imaging in infants with CHD.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0301-0449
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
518-22
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
MRI-based blood oxygen saturation measurements in infants and children with congenital heart disease.
pubmed:affiliation
Department of Paediatrics and Division of Cardiology, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada. lynne_nield@hotmail.com
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't