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rdf:type |
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|
lifeskim:mentions |
|
|
pubmed:issue |
14
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pubmed:dateCreated |
2002-7-5
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|
pubmed:abstractText |
The first total synthesis of aquatic peptide microcin SF608 is described. Coupling of L-Hpla with the dipeptide L-Phe-L-Choi followed by coupling with agmatine and a deprotection step gave microcin SF608. In addition, the levorotatory character of L-Hpla (5) was thoroughly established, and the conformational analysis of L-Choi containing peptides 1 and 8-10 was performed using NMR spectroscopy to examine the cis-trans isomer equilibrium of the L-Phe-L-Choi amide bond.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Jul
|
|
pubmed:issn |
0022-3263
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
12
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pubmed:volume |
67
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
4945-50
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12098309-Anti-Bacterial Agents,
pubmed-meshheading:12098309-Bacteriocins,
pubmed-meshheading:12098309-Catalysis,
pubmed-meshheading:12098309-Indoles,
pubmed-meshheading:12098309-Leucine,
pubmed-meshheading:12098309-Molecular Structure,
pubmed-meshheading:12098309-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:12098309-Peptides,
pubmed-meshheading:12098309-Stereoisomerism,
pubmed-meshheading:12098309-Trypsin Inhibitors
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|
pubmed:year |
2002
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|
pubmed:articleTitle |
Synthesis of microcin SF608.
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|
pubmed:affiliation |
Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, 08028-Barcelona, Spain.
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|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
