Source:http://linkedlifedata.com/resource/pubmed/id/12097468
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
2002-7-4
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| pubmed:abstractText |
Disease-specific genes of unknown function can be imaged in vivo with antisense radiopharmaceuticals, providing the transcellular transport of these molecules is enabled with drug-targeting technology. The current studies describe the production of 16-mer peptide nucleic acid (PNA) that is antisense around the methionine initiation codon of the huntingtin gene of Huntington's disease (HD).
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| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0161-5505
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
43
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
948-56
|
| pubmed:dateRevised |
2007-11-14
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| pubmed:meshHeading |
pubmed-meshheading:12097468-Animals,
pubmed-meshheading:12097468-Brain,
pubmed-meshheading:12097468-DNA, Antisense,
pubmed-meshheading:12097468-Drug Delivery Systems,
pubmed-meshheading:12097468-Gene Expression,
pubmed-meshheading:12097468-Huntington Disease,
pubmed-meshheading:12097468-Iodine Radioisotopes,
pubmed-meshheading:12097468-Mice,
pubmed-meshheading:12097468-Mice, Inbred BALB C,
pubmed-meshheading:12097468-Mice, Transgenic,
pubmed-meshheading:12097468-Peptide Nucleic Acids,
pubmed-meshheading:12097468-Radiopharmaceuticals
|
| pubmed:year |
2002
|
| pubmed:articleTitle |
Imaging gene expression in the brain in vivo in a transgenic mouse model of Huntington's disease with an antisense radiopharmaceutical and drug-targeting technology.
|
| pubmed:affiliation |
Department of Medicine, UCLA School of Medicine, 90024, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|