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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
13
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pubmed:dateCreated |
2002-7-3
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pubmed:abstractText |
Germline mutations in BRCA1 and BRCA2 are responsible for 5%-10% of epithelial ovarian cancers, but the molecular pathways affected by these mutations are unknown. We used complementary DNA (cDNA) microarrays to compare gene expression patterns in ovarian cancers associated with BRCA1 or BRCA2 mutations with gene expression patterns in sporadic epithelial ovarian cancers and to identify patterns common to both hereditary and sporadic tumors.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0027-8874
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
3
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pubmed:volume |
94
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
990-1000
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12096084-Adenocarcinoma, Clear Cell,
pubmed-meshheading:12096084-Adenocarcinoma, Mucinous,
pubmed-meshheading:12096084-Aged,
pubmed-meshheading:12096084-BRCA1 Protein,
pubmed-meshheading:12096084-BRCA2 Protein,
pubmed-meshheading:12096084-Carcinoma, Endometrioid,
pubmed-meshheading:12096084-Cystadenocarcinoma, Serous,
pubmed-meshheading:12096084-DNA Primers,
pubmed-meshheading:12096084-Female,
pubmed-meshheading:12096084-Gene Expression Profiling,
pubmed-meshheading:12096084-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:12096084-Genotype,
pubmed-meshheading:12096084-Germ-Line Mutation,
pubmed-meshheading:12096084-Humans,
pubmed-meshheading:12096084-Middle Aged,
pubmed-meshheading:12096084-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:12096084-Ovarian Neoplasms,
pubmed-meshheading:12096084-RNA, Messenger,
pubmed-meshheading:12096084-RNA, Neoplasm,
pubmed-meshheading:12096084-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2002
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pubmed:articleTitle |
Gene expression profiles of BRCA1-linked, BRCA2-linked, and sporadic ovarian cancers.
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pubmed:affiliation |
Division of Clinical Sciences of the National Cancer Institute, Gaithersburg, MD,USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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