Linked Life Data

12095325

Source:http://linkedlifedata.com/resource/pubmed/id/12095325

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
27
pubmed:dateCreated
2002-7-3
pubmed:abstractText
Tetraalaninecalixarene was prepared by coupling of tetraaminocalix[4]arene with alanine. It dimerizes in methanol, providing the first example of a substituted calixarene that undergoes self-association through hydrogen bonding in polar, protic solvent. The association constant in 24:1 MeOH:H2O was determined to be 29 000 M-1. Addition of arginine or lysine results in disruption of the dimer and formation of a 1:1 complex between the amino acid and the tetraalaninecalixarene. The preparation of a peptidocalixarene that associates in polar solvent opens new doors for the use of calixarenes for molecular recognition in biologically relevant environments.
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Jul
pubmed:issn
0002-7863
pubmed:author
pubmed:issnType
Print
pubmed:day
10
pubmed:volume
124
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7902-3
pubmed:dateRevised
2008-1-17
pubmed:year
2002
pubmed:articleTitle
Molecular recognition in methanol: the first example of hydrogen-bond-mediated self-association of a calix[4]arene in polar, protic solvent.
pubmed:affiliation
School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30329-0400, USA.
pubmed:publicationType
Journal Article