rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
2002-7-3
|
pubmed:abstractText |
Balsalazide is a new innovative, mesalamine-containing prodrug that is activated by bacteria in the colon. Balsalazide has been shown previously to be well tolerated and effective in the treatment of acute ulcerative colitis. The aim of this study was to determine the dose-response of balsalazide for efficacy and safety in active, mild-to-moderate ulcerative colitis and to compare this profile with that of mesalamine, pH-dependent, delayed-release tablets.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0002-9270
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
97
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1398-407
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12094857-Adult,
pubmed-meshheading:12094857-Aged,
pubmed-meshheading:12094857-Aged, 80 and over,
pubmed-meshheading:12094857-Aminosalicylic Acids,
pubmed-meshheading:12094857-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:12094857-Anti-Ulcer Agents,
pubmed-meshheading:12094857-Colitis, Ulcerative,
pubmed-meshheading:12094857-Dose-Response Relationship, Drug,
pubmed-meshheading:12094857-Double-Blind Method,
pubmed-meshheading:12094857-Female,
pubmed-meshheading:12094857-Homeostasis,
pubmed-meshheading:12094857-Humans,
pubmed-meshheading:12094857-Male,
pubmed-meshheading:12094857-Mesalamine,
pubmed-meshheading:12094857-Middle Aged,
pubmed-meshheading:12094857-Phenylhydrazines,
pubmed-meshheading:12094857-Safety,
pubmed-meshheading:12094857-Severity of Illness Index
|
pubmed:year |
2002
|
pubmed:articleTitle |
A randomized, double blind, dose-response comparison of balsalazide (6.75 g), balsalazide (2.25 g), and mesalamine (2.4 g) in the treatment of active, mild-to-moderate ulcerative colitis.
|
pubmed:affiliation |
Division of Gastroenterology, University of Washington School of Medicine, Seattle, USA.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Multicenter Study
|