Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2002-7-3
pubmed:abstractText
Based on the genetic and epigenetic abnormalities of cancer-related genes during the development and progression of gastric cancer, we have established a system of molecular-pathological diagnosis as a routine service in Hiroshima. Approximately 5,000 lesions of the stomach have been diagnosed and useful information on differential diagnosis, grade of malignancy, and tumor multiplicity has been obtained using this system. Further research on systemic gene expression profiles, epigenetic alterations, and genetic polymorphisms will improve the quality and efficiency of diagnosis. With the application of novel knowledge on molecular carcinogenesis and microarray techniques, molecular diagnosis will identify the characteristics of individual cancers and persons, which will lead to the development of personalized medicine.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0301-4894
pubmed:author
pubmed:issnType
Print
pubmed:volume
103
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
463-7
pubmed:dateRevised
2011-7-26
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
[Molecular diagnosis of gastric cancer].
pubmed:affiliation
Department of Molecular Pathology, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan.
pubmed:publicationType
Journal Article, English Abstract