Linked Life Data

12094539

Source:http://linkedlifedata.com/resource/pubmed/id/12094539

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2002-7-3
pubmed:abstractText
Only 16 cases of breast carcinoma in human immunodeficiency virus (HIV) seropositive patients have been reported in the literature. We report four cases of breast cancer in women seropositive for the HIV and review the literature. Breast cancer is not an acquired immunodeficiency syndrome (AIDS)-defining disease and its incidence is not increased in HIV patients. Most patients reported had a CD4 count, which was above the threshold considered critical for significant immunosuppression suggesting that, HIV related immunocompromise does not have a direct tumorigenic role. Alternatively, the biology of breast cancer appears to be more aggressive in HIV-positive women suggesting a permissive role of the virus in the progression of the cancer. The aggressiveness of the breast carcinoma in HIV-positive women justifies every effort to preserve the dose intensity of treatment in those patients, especially in the current era of more effective HIV treatment which leads to improved survival.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0735-7907
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
452-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Breast cancer in HIV-positive women: a report of four cases and review of the literature.
pubmed:affiliation
Division of Hematology, Division of Medical Oncology, Department of Medicine, Mount Sinai Hospital, Mount Sinai School of Medicine, New York, New York, USA. voutsadakis@igr.fr
pubmed:publicationType
Journal Article, Review, Case Reports, Research Support, Non-U.S. Gov't