Source:http://linkedlifedata.com/resource/pubmed/id/12089165
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
2002-6-28
|
| pubmed:abstractText |
NO synthesized from L-arginine by the constitutive endothelial NO synthase (eNOS) plays a key role in the atherosclerotic process. We investigated whether common variants in the NOS3 gene (a T786C mutation in the 5' flanking region and the polymorphism on exon 7 that produced the Glu298Arg polymorphism in the protein) are associated with an increased risk of moderate to severe internal carotid artery (ICA) stenosis.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0009-9147
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
48
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
989-93
|
| pubmed:dateRevised |
2005-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:12089165-Aged,
pubmed-meshheading:12089165-Carotid Artery Diseases,
pubmed-meshheading:12089165-Constriction, Pathologic,
pubmed-meshheading:12089165-Female,
pubmed-meshheading:12089165-Humans,
pubmed-meshheading:12089165-Male,
pubmed-meshheading:12089165-Middle Aged,
pubmed-meshheading:12089165-Nitric Oxide Synthase,
pubmed-meshheading:12089165-Nitric Oxide Synthase Type III,
pubmed-meshheading:12089165-Polymerase Chain Reaction,
pubmed-meshheading:12089165-Polymorphism, Genetic,
pubmed-meshheading:12089165-Risk Factors,
pubmed-meshheading:12089165-Severity of Illness Index
|
| pubmed:year |
2002
|
| pubmed:articleTitle |
Independent risk factor for moderate to severe internal carotid artery stenosis: T786C mutation of the endothelial nitric oxide synthase gene.
|
| pubmed:affiliation |
Dipartimento di Medicina, Chirurgia e Odontoiatria, Clinica Chirurgica Generale, Università degli Studi di Milano-Polo S. Paolo, Via A. Di Rudinì 8, I-20142 Milan, Italy. giorgio.ghilardi@unimi.it
|
| pubmed:publicationType |
Journal Article
|