Source:http://linkedlifedata.com/resource/pubmed/id/12088676
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2002-6-28
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pubmed:abstractText |
Type I interferon (IFN-alpha/beta) is expressed rapidly following exposure to a wide variety of infectious agents and plays a key role in innate control of virus replication. Recent studies have demonstrated that dendritic cells both produce IFN-alpha/beta and undergo maturation in response to IFN-alpha/beta. Moreover, IFN-alpha/beta has been shown to potently enhance immune responses in vivo through the stimulation of dendritic cells. These findings indicate that IFN-alpha/beta serves as a signal linking innate and adaptive immunity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0952-7915
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
432-6
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:12088676-Adjuvants, Immunologic,
pubmed-meshheading:12088676-Animals,
pubmed-meshheading:12088676-Dendritic Cells,
pubmed-meshheading:12088676-Humans,
pubmed-meshheading:12088676-Immunity, Innate,
pubmed-meshheading:12088676-Infection,
pubmed-meshheading:12088676-Interferon Type I,
pubmed-meshheading:12088676-Lymphocyte Activation,
pubmed-meshheading:12088676-Models, Immunological
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pubmed:year |
2002
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pubmed:articleTitle |
Links between innate and adaptive immunity via type I interferon.
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pubmed:affiliation |
The Edward Jenner Institute for Vaccine Research, Compton, Newbury, Berkshire, UK. agnes.lebon@jenner.ac.uk
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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