Linked Life Data

12082347

Source:http://linkedlifedata.com/resource/pubmed/id/12082347

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2002-6-25
pubmed:abstractText
The purposes of the present study were to track the geographic spread of 69 MRSA strains in Italy recovered from 7 hospitals in four towns; to detect the clonal identities among the isolates by a combination of multiple genomic typing methods and to measure temporal trends in clonal types between 1984 and 1998. Our results showed the spread of three major clones among the MRSA isolates of 1984-1995 period: the most represented MRSA clone carried the PFGE pattern A, the mecA polymorph II and had no homology with Tn554 (II::NH::A); most of these isolates were susceptible to the macrolides,being similar to the historically " archaic" MRSA strains; the clone typed I::E::A, carried the PFGE pattern A, the mecA polymorph I and Tn554E commonly defined as "Iberian clone"; unique clone, showing an uncommon PFGE pattern E. the mecA polymorph II and the Tn554 E (II::E::E) and were characterized by a uniform susceptibility to tetracycline and rifampin. During 1997-98 the representation of this clone increased instead of the classical "Iberian clone". A new multi-resistant MRSA strain, carrying the PFGE pattern B (or B'), the mecA polymorph XI and Tn554 polymorph B (XI::B::B), called "Brazilian clone", increased from being absent (1984-95) to 48%. Our molecular data show an Italian MRSA "scenario" far from the common European trends and clearly documented the spread of an archaic clonal type (II::NH::A) in 1984-95, the arrival and rapid increase of Brazilian done in 1997-98 and the chronological and geographical spread of a unique (H::E::E) called "Italian clone", instead of the widely spread Iberian MRSA clone.
pubmed:language
ita
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1124-9390
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
30-8
pubmed:dateRevised
2007-12-5
pubmed:meshHeading
pubmed-meshheading:12082347-Bacterial Proteins, pubmed-meshheading:12082347-Carrier Proteins, pubmed-meshheading:12082347-Cross Infection, pubmed-meshheading:12082347-DNA, Bacterial, pubmed-meshheading:12082347-DNA Mutational Analysis, pubmed-meshheading:12082347-DNA Transposable Elements, pubmed-meshheading:12082347-Drug Resistance, Multiple, Bacterial, pubmed-meshheading:12082347-Electrophoresis, Gel, Pulsed-Field, pubmed-meshheading:12082347-Evolution, Molecular, pubmed-meshheading:12082347-Genes, Bacterial, pubmed-meshheading:12082347-Genotype, pubmed-meshheading:12082347-Hexosyltransferases, pubmed-meshheading:12082347-Italy, pubmed-meshheading:12082347-Methicillin Resistance, pubmed-meshheading:12082347-Microbial Sensitivity Tests, pubmed-meshheading:12082347-Muramoylpentapeptide Carboxypeptidase, pubmed-meshheading:12082347-Penicillin-Binding Proteins, pubmed-meshheading:12082347-Peptidyl Transferases, pubmed-meshheading:12082347-Polymorphism, Genetic, pubmed-meshheading:12082347-Staphylococcal Infections, pubmed-meshheading:12082347-Staphylococcus aureus, pubmed-meshheading:12082347-Time Factors
pubmed:year
2001
pubmed:articleTitle
[Clonal diffusion and evolution of mecA and Tn554 polymorphisms in methicillin-resistant Staphylococcus aureus in Italy].
pubmed:affiliation
Dipartimento di Scienze Microbiologiche e Scienze Ginecologiche Sezione di Microbiologia, Universit degli Studi di Catania.
pubmed:publicationType
Journal Article, English Abstract