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pubmed-article:12081583pubmed:abstractTextTraditional blood and urine markers for the diagnosis of various renal diseases are insensitive and nonspecific. Kidney Injury Molecule-1 (KIM-1) is a type 1 transmembrane protein, with an immunoglobulin and mucin domain, whose expression is markedly up-regulated in the proximal tubule in the post-ischemic rat kidney. The ectodomain of KIM-1 is shed from cells. The current studies were carried out to evaluate whether KIM-1 is present in human acute renal failure and might serve as a urinary marker of acute renal tubular injury.lld:pubmed
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pubmed-article:12081583pubmed:articleTitleKidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury.lld:pubmed
pubmed-article:12081583pubmed:affiliationMedical Services, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.lld:pubmed
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pubmed-article:12081583pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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