Source:http://linkedlifedata.com/resource/pubmed/id/12081583
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2002-6-25
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pubmed:abstractText |
Traditional blood and urine markers for the diagnosis of various renal diseases are insensitive and nonspecific. Kidney Injury Molecule-1 (KIM-1) is a type 1 transmembrane protein, with an immunoglobulin and mucin domain, whose expression is markedly up-regulated in the proximal tubule in the post-ischemic rat kidney. The ectodomain of KIM-1 is shed from cells. The current studies were carried out to evaluate whether KIM-1 is present in human acute renal failure and might serve as a urinary marker of acute renal tubular injury.
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pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0085-2538
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
237-44
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:12081583-Acute Kidney Injury,
pubmed-meshheading:12081583-Aged,
pubmed-meshheading:12081583-Aged, 80 and over,
pubmed-meshheading:12081583-Biological Markers,
pubmed-meshheading:12081583-Cell Adhesion Molecules,
pubmed-meshheading:12081583-Female,
pubmed-meshheading:12081583-Humans,
pubmed-meshheading:12081583-Kidney Tubular Necrosis, Acute,
pubmed-meshheading:12081583-Kidney Tubules, Proximal,
pubmed-meshheading:12081583-Male,
pubmed-meshheading:12081583-Membrane Proteins,
pubmed-meshheading:12081583-Middle Aged
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pubmed:year |
2002
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pubmed:articleTitle |
Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury.
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pubmed:affiliation |
Medical Services, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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